Drug Discovery & Chemical Biology
Platform services
Drug discovery and chemical biology
- Project and assay guidance and development support
- Chemical screening
- Drug sensitivity and resistance screening (DSRT) and drug repurposing
- Chemoinformatics, molecular modeling and virtual screening
- Follow-up screening and testing
- Access to a large national chemical collectionAccess to a large national chemical collection
- Translation
- Training
The drug discovery and chemical biology (DDCB) platform provides coordinated services in assay development and chemical screening - from low- to ultra-high throughput - with a broad range of readouts and assay types including the DDCB-developed drug sensitivity and resistance testing, antibacterial screening, cell-free and cell-based protein-protein interaction assays, virtual screening, chemoinformatics, follow-up (specialized) assays. DDCB offers also open access to a large national chemical collection, drug testing and repurposing of drugs, translational support and user base education. Several of the services represent unique opportunities for the biomedical community that are not found elsewhere and are very strong in the European scale.
Drug discovery and chemical biology
Drug discovery and chemical biology platform website: https://www.helsinki.fi/en/infrastructures/drug-discovery-and-chemical-biology-consortium
Project and assay guidance and development support
Helsinki Institute of Life Science - HiLIFE
Faculty of Pharmacy
FIMM High Throughput Biomedicine Unit
Biocenter Kuopio
Drug Design and Synthesis Laboratory
BioCity Turku
Turku Screening Unit
Chemical screening
Helsinki Institute of Life Science - HiLIFE
Faculty of Pharmacy
FIMM High Throughput Biomedicine Unit
BioCity Turku
Turku Screening Unit
Drug sensitivity and resistance screening (DSRT) and drug repurposing
Helsinki Institute of Life Science - HiLIFE
FIMM High Throughput Biomedicine Unit
Chemoinformatics, molecular modeling and virtual screening
Helsinki Institute of Life Science - HiLIFE
Faculty of Pharmacy
Biocenter Kuopio
Drug Design and Synthesis Laboratory
BioCity Turku
Turku Screening Unit
Follow-up screening and testing
Helsinki Institute of Life Science - HiLIFE
Faculty of Pharmacy
FIMM High Throughput Biomedicine Unit
Biocenter Kuopio
Drug Design and Synthesis Laboratory
Access to a large national chemical collection
For more information please, visit DDCB website
Translation
To facilitate translation of user discoveries into commercial and translational space, a translational technologies advisory board has been linked to the DDCB network.
DDCB further links to external medicinal and organic chemistry groups, for example, through European infrastructure consortia EU OPENSCREEN and EATRIS.
Training
Helsinki Institute of Life Science - HiLIFE
Faculty of Pharmacy
FIMM High Throughput Biomedicine Unit
BioCity Turku
Turku Screening Unit
Contact persons
Platform Chair
Päivi Tammela, HiLIFE - FIMM & Faculty of Pharmacy, University of Helsinki
Platform partners
Arto Urtti, HiLIFE - Faculty of Pharmacy, University of Helsinki;
Antti Poso, BCK, Drug Design and Synthesis Laboratory, University of Eastern Finland;
Michael Courtney, Turku Screening Unit & Turku Bioscience Centre, University of Turku
Affiliated expert members: Antti Pursula, CSC