Symposium: Building Bridges 2021 - Technologies advancing molecular medicine – focus on Nordic infrastructures

The Nordic EMBL Partnership warmly invites you to participate in the tenth Building Bridges symposium providing an exciting collaborative look into advanced research technologies. The Building Bridge series is aimed to highlight collaborative efforts towards, ultimately, a better understanding of the pathophysiology of disease and improved options for patient treatment and care. 

Building Bridges 2021:  Technologies advancing molecular medicine – focus on Nordic infrastructures

The Building Bridges symposia series is arranged to bridge basic, translational and clinical research and provide examples of how teams of investigators are working together to advance molecular medicine.  With the 10th Building Bridges symposium we shine the spotlight on technologies used to improve our understanding of health and disease.  In particular, we will demonstrate research advances using infrastructure available in the Nordic region, bridging research and technology development as well as bridging researchers across borders. With an opening and closing keynote from EMBL Heidelberg and EMBL Hamburg, we highlight research infrastructure at EMBL, as well.

Join the symposium and learn more about the research technology and core facility services available within the Nordic EMBL Partnership!

Organizers: The Nordic EMBL Partnership for Molecular Medicine, a Nordforsk-funded Research Infrastructure Hub. The Nordic EMBL Partnership consists of four international research and technology centers:

  • Danish Research Institute of Translational Neuroscience (DANDRITE)
  • Institute for Molecular Medicine Finland (FIMM)
  • The Laboratory for Molecular Infection Medicine Sweden (MIMS)
  • Centre for Molecular Medicine Norway (NCMM)

Venue: Hybrid
On-site: University of Helsinki, Meilahti Campus, Biomedicum 1, Lecture Hall 2
Online via Zoom: link and passcode provided in registration confirmation
Webpage
https://bit.ly/3jkG5vl
Date and time: Wednesday, 1 December 2021 at 9:00-16:00 CET/10.00-17.00 EET

Program: 

9.00

Welcome from the organizers & setting the stage

Katja Kivinen, FIMM

 

Session I:  High resolution technologies in molecular medicine

Chairs:  Pirkko Mattila, FIMM

9.10

Opening Keynote: From genotype to phenotype with single-cell resolution
Oliver Stegle (DKFZ & EMBL Heidelberg)

9.45

Single cell analysis for precision cancer medicine
Caroline Heckman (FIMM)

10.10

Discovery of novel anti-chlamydial compounds through a multi-strategy screening approach
Barbara Sixt (MIMS)

10.35

Break, coffee & tea

11.00

Aarhus CryoEM - on the path to in situ structural biology
Thomas Boesen (DANDRITE)

11.25

Inherited causes of somatic mutagenesis and evolution in cancer
Sebastian Martin Waszak (NCMM)

11.50

Short pitches for research visits

CryoEM structures of centromeric complexes – collaboration between NCMM and cryoEM facility in Umeå (MIMS)
Ahmad Ali-Ahmad (NCMM)

Defining dietary effects on mouse gut microbiota metabolites with metabolomics
Björn Schröder (MIMS) & Anni Nieminen (FIMM)

Patient-derived slice-model as a low throughput screening method
Nanna Møller Jensen (DANDRITE)

Collaborations with Chemical Biology Consortium Sweden (CBCS): The Swedish national platform for small molecule screening
Anna Eriksson (CBCS)

Phenotypic screening of patient -derived primary cells (FIMM-NCMM collaboration)
Antti Hassinen (FIMM)

   

12.20

Lunch (light lunch provided for those attending on-site)

   

Session II:  Models, characterizations and structures

Chair:  Thomas Boesen (DANDRITE)

13.15

Diagnostic modelling in the context of cancer heterogeneity
Emmy Verschuren (FIMM) & Sarang Talwelkar (FIMM)

13.40

Unbiased characterization of cells using single-cell analysis
Johan Henriksson (MIMS)

14.05

The zebrafish as a model organism to understand and treat complex genetic disorders
Camilla Esguerra (NCMM)

14.30

Break, coffee & tea

15.00

Lipid flippase CryoEM structure case: structure-based drug development and translational collaboration with hospitals/medical doctors
Thibaud Dieudonne (DANDRITE)

15.25

Closing keynote: EMBL Imaging Centre: the technology development we need for the imaging challenges we face
Simone Mattei (EMBL Hamburg)

16.00

Closing words
Organizing committee led by Katja Kivinen

ECTS credits: 1,0 ECTS - University of Helsinki doctoral candidates who would like to earn 1,0 ECTS are required to attend the symposium and complete advance readings and follow-up quiz questions provided for each talk. Further information about the advance readings and quiz will be posted on the course webpage as soon as available.

Registration:
University of Helsinki doctoral candidates must register in SISU, course code DPBM-194
All others, please register using the e-form: https://elomake.helsinki.fi/lomakkeet/53957/lomake.html
Registration deadline:  21 November

Organizing Team:
Heidi Arling, FIMM, Tämä sähköpostiosoite on suojattu spamboteilta. Tarvitset JavaScript-tuen nähdäksesi sen.
Thomas Boesen, DANDRITE, Tämä sähköpostiosoite on suojattu spamboteilta. Tarvitset JavaScript-tuen nähdäksesi sen.
Katja Kivinen, FIMM, Tämä sähköpostiosoite on suojattu spamboteilta. Tarvitset JavaScript-tuen nähdäksesi sen.
Pirkko Mattila, FIMM, Tämä sähköpostiosoite on suojattu spamboteilta. Tarvitset JavaScript-tuen nähdäksesi sen.
Vilja Pietiäinen, FIMM, vilja.pietiäTämä sähköpostiosoite on suojattu spamboteilta. Tarvitset JavaScript-tuen nähdäksesi sen.
Gretchen Repasky, Nordic EMBL Partnership/FIMM, Tämä sähköpostiosoite on suojattu spamboteilta. Tarvitset JavaScript-tuen nähdäksesi sen.
Nikolina Sekulic, NCMM, Tämä sähköpostiosoite on suojattu spamboteilta. Tarvitset JavaScript-tuen nähdäksesi sen.
Barbara Sixt, MIMS, Tämä sähköpostiosoite on suojattu spamboteilta. Tarvitset JavaScript-tuen nähdäksesi sen.

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